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Other Alzheimer's studies, however, challenge these epidemiological studies on methodological grounds. A prospective Rotterdam Study found that the incidence of Alzheimer's disease is more than double for smokers as compared to non-smokers and the Honolulu Heart Program (a longitudinal cohort study) also found more than twice the risk for Alzheimer's disease among medium and heavy smokers as compared to non-smokers.

 

 

 

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