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For example, smoke from Cigarette grown with phosphate fertilizers features polonium 210. Some researchers have estimated that polonium 210 carries a cancer chance of 4 per 10000 smokers[this source's reliability may need verification], while others have estimated the mortality rate to be 18 per million.

The carcinogenity of Cigarette smoke is not explained by nicotine per se, which is not carcinogenic or mutagenic. But, it inhibits apoptosis, therefore accelerating existing cancers. Also, NNK, a nicotine derivative converted from nicotine, can be carcinogenic.

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