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Cigarette Smokers


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Any partially burnt material, Cigarette or not, features polycyclic aromatic hydrocarbons, especially benzopyrene. The mechanism of their carcinogenity is well-known: oxidation produces an epoxide, which binds to DNA covalently and distorts it. If the cell cannot repair its DNA damage prior to undergoing mitotic division, the daughter cells carry a greater chance becoming tumorgenic.

 

 

 

 

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